Praxis Precision Medicines and Remagine Labs Announce Strategic Collaboration to Develop Transdermal Ulixacaltamide for Essential Tremor
Collaboration aims to quickly enable ulixacaltamide to be delivered via active transdermal route
Potential to expand the addressable market for ulixacaltamide beyond the initial patient population and to enable additional life-cycle management opportunities
Praxis to make equity investment in
Ulixacaltamide is Praxis's lead asset in ET and the most clinically advanced therapy in the field. The FDA accepted the ulixacaltamide New Drug Application (NDA) for ET in
ET affects approximately seven million people in
Under the agreement, Praxis and Remagine will collaborate to apply Remagine's proprietary platform, designed for precise, multi-day active transdermal dosing, to ulixacaltamide, complementing Praxis's lead oral program. A transdermal option is intended to broaden the population ulixacaltamide can reach, while strengthening ulixacaltamide's competitive positioning and extending the long-term value of the franchise. Praxis has also made an equity investment in
“Ulixacaltamide is poised to be the first new therapy for essential tremor in decades, and we are already building for its future,” said
“We are excited to collaborate with Praxis, a company with deep expertise in developing innovative therapies for central nervous system disorders,” said
About
About Remagine Labs
Remagine Labs is an Austin, Texas and Melbourne, Australia-based drug delivery technology company developing wearable, electronically controlled transdermal drug delivery systems. The company's platform is designed to provide precise, programmable dosing of pharmaceutical compounds through the skin, enabling new approaches to the treatment of neurological and other conditions. Remagine is supported by the University of Melbourne, Monash University, the Genesis Pre-Seed Fund, Innovation Victoria, and the Australian Government's Cooperative Research Centres Program. For more information, visit www.remaginelabs.com.
Forward-Looking Statements
This press release contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995 and other federal securities laws, including express or implied statements regarding Praxis’ future expectations, plans and prospects, including, without limitation, statements regarding Praxis’s strategic collaboration with Remagine and the development and potential market opportunity of ulixacaltamide, as well as other statements containing the words “anticipate,” “believe,” “continue,” “could,” “endeavor,” “estimate,” “expect,” “intend,” “may,” “might,” “plan,” “potential,” “predict,” “project,” “seek,” “should,” “target,” “will” or “would” and similar expressions that constitute forward-looking statements under the Private Securities Litigation Reform Act of 1995.
The express or implied forward-looking statements included in this press release are only predictions and are subject to a number of risks, uncertainties and assumptions, including, without limitation: uncertainties related to submissions for regulatory approval or review by governmental authorities, uncertainties related to activities with collaboration partners, and other risks concerning Praxis’ programs and operations as described in its Annual Report on Form 10-K for the year ended December 31, 2025 and other filings made with the Securities and Exchange Commission. Although Praxis’ forward-looking statements reflect the good faith judgment of its management, these statements are based only on information and factors currently known by Praxis. As a result, you are cautioned not to rely on these forward-looking statements. Any forward-looking statement made in this press release speaks only as of the date on which it is made. Praxis undertakes no obligation to publicly update or revise any forward-looking statement, whether as a result of new information, future developments or otherwise.
Media Contact — Remagine Labs Pat Kelly pkelly@remaginelabs.com 512-633-6878 Media Contact — Praxis Precision Medicines Investor Contact: Praxis Precision Medicines investors@praxismedicines.com 857-702-9452 Media Contact: Dan Ferry LifeSci Advisors Daniel@lifesciadvisors.com 617-430-7576
